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August 22, 2020

Diffusion susceptibility tests of norfloxacin performed by the ICS

By Alejandra

Standards for interpretation of agar diffusion susceptibility checks of norfloxacin carried out by the ICS technique.

Utilizing regression evaluation to correlate MIC values and inhibition zone diameters, an try was made to ascertain standards for decoding the outcomes of the agar diffusion take a look at with norfloxacin discs (10 mcg). The take a look at was carried out on DST agar in accordance with ICS suggestions.

The correlation was average (r = -0.8547); the regression equation was x = -0.30y + 15.80, the place x was log2 MIC + 9 and y the inhibition zone diameter. The place of the MIC breakpoints of norfloxacin and the distribution of the MIC values of the bacterial inhabitants didn’t allow exact inhibition zone breakpoints to be established. To permit a security margin it is suggested that for the meantime norfloxacin inhibition zones be interpreted as delicate from 15 mm onwards.

 

The impact of EC-IC bypass surgical procedure on resting cerebral blood move and cerebrovascular reserve capability studied with steady XE-CT and acetazolamide take a look at.

  • Cerebral blood move (CBF) and cerebrovascular reserve capability (CRC) have been measured by steady xenon computerized tomography (Xe-CT) and acetazolamide take a look at in 15 sufferers with cerebrovascular illness earlier than and after extracranial-intracranial (EC-IC) bypass surgical procedure for minor stroke, reversible ischemic neurological deficit or transient ischemic assault. All had angiographically proven occlusive lesions of the most important arterial trunk.
  • Within the current collection, world evaluation confirmed that the bypass didn’t enhance the resting rCBF, however did enhance the rCRC. We divided the sufferers into 4 teams in line with the preoperative resting rCBF and rCRC. All Three sufferers with regular resting rCBF and diminished rCRC confirmed postoperative enchancment of rCRC.
  • Of 6 sufferers with diminished CBF and diminished CRC, three had postoperative enhance in resting CBF and 4 had elevated CRC.
  • One among two sufferers with diminished CBF and regular CRC confirmed solely a rise in CRC. We suggest that diminished CRC or diminished CBF with diminished CRC are standards for number of candidates for bypass surgical procedure.
  • We conclude that Xe-CT with the Diamox take a look at is a helpful and easy technique for evaluating cerebral hemodynamics. Preoperative grouping with a mixture of preoperative resting rCBF and preoperative rCRC is beneficial for predicting the impact of EC-IC bypass surgical procedure.
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Sheep Intestine Genomic DNA
SG-306 0.1mg
EUR 177

Bovine Intestine Genomic DNA
BG-306 0.1mg
EUR 177

Equine Intestine Genomic DNA
GE-306 0.1mg
EUR 210

Rabbit Intestine Genomic DNA
TG-306 0.1mg
EUR 177

Hamster Intestine Genomic DNA
GA-306 0.1mg
EUR 177

Chicken Intestine Genomic DNA
GC-306 0.1mg
EUR 177

Mouse C57 Intestine Genomic DNA
MG-306-C57 0.1mg
EUR 210

Monkey Rhesus Intestine Genomic DNA
UG-306 0.1mg
EUR 210

Monkey Cynomolgus Intestine Genomic DNA
KG-306 0.1mg
EUR 210

Genomic DNA - Rat Normal Tissue: Small Intestine
D1434226 100 ug
EUR 329

Genomic DNA - Mouse Normal Tissue: Small Intestine
D1334226 100 ug
EUR 329

Genomic DNA - Lupus: Small Intestine, from a single donor
D1236226Lup 50 ug
EUR 580

Tissue, Genomic DNA, Rat Adult Normal, Small Intestine, BioGenomics
MBS654493-01mg 0.1mg
EUR 575

Tissue, Genomic DNA, Rat Adult Normal, Small Intestine, BioGenomics
MBS654493-5x01mg 5x0.1mg
EUR 2440

Tissue, Genomic DNA, Mouse Adult Normal, Small Intestine, BioGenomics
MBS654631-01mg 0.1mg
EUR 575

Tissue, Genomic DNA, Mouse Adult Normal, Small Intestine, BioGenomics
MBS654631-5x01mg 5x0.1mg
EUR 2440

Tissue, Genomic DNA, Human Adult Normal, Small intestine, BioGenomics
MBS654400-01mg 0.1mg
EUR 575

Tissue, Genomic DNA, Human Adult Normal, Small intestine, BioGenomics
MBS654400-5x01mg 5x0.1mg
EUR 2440

Tissue, Genomic DNA, Human Disease, Lupus, Small intestine, BioGenomics
MBS654503-005mg 0.05mg
EUR 725

Tissue, Genomic DNA, Human Disease, Lupus, Small intestine, BioGenomics
MBS654503-5x005mg 5x0.05mg
EUR 3115

Genomic DNA - Liver Cirrhosis: Small Intestine, from a single donor
D1236226Lcs 50 ug
EUR 562

Tissue, Genomic DNA, Human Disease, Liver Cirrhosis, Small intestine, BioGenomics
MBS654392-005mg 0.05mg
EUR 715

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MBS654392-5x005mg 5x0.05mg
EUR 3075

Genomic DNA - Human Adult Normal Tissue: Small Intestine, from a single donor
D1234226 100 ug
EUR 329

Tissue, Genomic DNA, Human Disease (Adult), Diabetes, Small Intestine, Ileum, BioGenomics
MBS654563-005mg 0.05mg
EUR 715

Tissue, Genomic DNA, Human Disease (Adult), Diabetes, Small Intestine, Ileum, BioGenomics
MBS654563-5x005mg 5x0.05mg
EUR 3075

Tissue, Genomic DNA, Human Disease (Adult), Diabetes, Small Intestine, Jejunum, BioGenomics
MBS654618-005mg 0.05mg
EUR 715

Tissue, Genomic DNA, Human Disease (Adult), Diabetes, Small Intestine, Jejunum, BioGenomics
MBS654618-5x005mg 5x0.05mg
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Mini Pig Skin Genomic DNA
GN-101 0.1mg
EUR 210

Mini Pig Lung Genomic DNA
GN-601 0.1mg
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Mini Pig Brain Genomic DNA
GN-201 0.1mg
EUR 210

Mini Pig Colon Genomic DNA
GN-311 0.1mg
EUR 210

Mini Pig Liver Genomic DNA
GN-314 0.1mg
EUR 210

Mini Pig Ovary Genomic DNA
GN-406 0.1mg
EUR 210

Mini Pig Heart Genomic DNA
GN-801 0.1mg
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Tissue, Genomic DNA, Human Disease (Adult), Diabetes, Small Intestine, Duodenum, BioGenomics
MBS654538-005mg 0.05mg
EUR 715

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MBS654538-5x005mg 5x0.05mg
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Mini Pig Testis Genomic DNA
GN-401 0.1mg
EUR 210

Mini Pig Uterus Genomic DNA
GN-411 0.1mg
EUR 210

Mini Pig Spleen Genomic DNA
GN-701 0.1mg
EUR 210

Mini Pig Kidney Genomic DNA
GN-901 0.1mg
EUR 210

Tissue, Genomic DNA, Human Adult Normal, Small Intestine, Ileum, Single Donor, BioGenomics
MBS654633-01mg 0.1mg
EUR 575

Tissue, Genomic DNA, Human Adult Normal, Small Intestine, Ileum, Single Donor, BioGenomics
MBS654633-5x01mg 5x0.1mg
EUR 2440

Mini Pig Stomach Genomic DNA
GN-302 0.1mg
EUR 210

Mini-pig Genomic DNA
GM-130 0.1mg
EUR 177

Mini Pig Pancreas Genomic DNA
GN-313 0.1mg
EUR 210

Mini Pig Esophagus Genomic DNA
GN-301 0.1mg
EUR 210

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Ileum, from a single donor
D1236227Dia 50 ug
EUR 562

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Jejunum, from a single donor
D1236230Dia 50 ug
EUR 562

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Duodenum, from a single donor
D1236101Dia 50 ug
EUR 562

Mini Pig Skeletal Muscles Genomic DNA
GN-102 0.1mg
EUR 210

Plant Genomic DNA Mini
GPG1001 50 preps
EUR 205.19

Plant Genomic DNA Mini
GPG1002 250 preps
EUR 969.53

B/T Genomic DNA Mini
GG1001 50 preps
EUR 174.32

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gBAC MINI GENOMIC DNA KIT
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IB47291 100 PREP KIT
EUR 269.93

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IB47292 300 PREP KIT
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gSWAB MINI GENOMIC DNA KIT
IB47275 4 PREP SAMPLE KIT
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gSWAB MINI GENOMIC DNA KIT
IB47276 100 PREP KIT
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IB47277 300 PREP KIT
EUR 864.39

Genomic DNA Mini Kit (Plant)
GP004 each
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Genomic DNA Mini Kit (Plant)
GP100 each
EUR 97

Genomic DNA Mini Kit (Tissue)
GT004 each
EUR 3

Genomic DNA Mini Kit (Tissue)
GT050 each
EUR 63.5

Genomic DNA Mini Kit (Tissue)
GT100 each
EUR 105

Genomic DNA Mini Kit (Tissue)
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EUR 283.5

MINI GENOMIC DNA KIT-PLANT
IB47230 4 PREP SAMPLE KIT
EUR 30.42

MINI GENOMIC DNA KIT-PLANT
IB47231 100 PREP KIT
EUR 382.97

MINI GENOMIC DNA KIT-PLANT
IB47232 300 PREP KIT
EUR 824.79

MINI GENOMIC DNA KIT-TISSUE
IB47220 4 PREP SAMPLE KIT
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MINI GENOMIC DNA KIT-TISSUE
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EUR 191.55

MINI GENOMIC DNA KIT-TISSUE
IB47222 300 PREP KIT
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Mini Pig Tissue Genomic DNA Panel, set of any 5 Tissues
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Mini Pig Tissue Genomic DNA Panel, set of any 10 Tissues
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Mini Pig Tissue Genomic DNA Panel, set of any 15 Tissues
GN-015 15X0.025mg
EUR 1557

MINI GENOMIC DNA KIT-BLOOD/CC
IB47200 4 PREP SAMPLE KIT
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MINI GENOMIC DNA KIT-BLOOD/CC
IB47201 100 PREP KIT
EUR 240.66

MINI GENOMIC DNA KIT-BLOOD/CC
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T-Pro Genomic DNA Mini Kit (100)
RB94-NGS100 100preps/kit
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Blood Genomic DNA Mini Kit (0.1-1ml)
MBS278035-50Preps 50Preps
EUR 215

MINI GENOMIC DNA COLUMNS & COLLECTION TUBES
IB47205 25/PACK
EUR 46.99

MINI GENOMIC DNA COLUMNS & COLLECTION TUBES
IB47206 50/PACK
EUR 84.61

MINI GENOMIC DNA COLUMNS & COLLECTION TUBES
IB47207 100/PACK
EUR 150.39

Genomic DNA Extraction Mini KitPlant Tissue
FYG103-100P 100 Preps Ask for price

Genomic DNA Mini Kit (Blood/Cultured Cell)
GB004 each
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Genomic DNA Mini Kit (Blood/Cultured Cell)
GB100 each
EUR 70

 

LD50 worth, phototoxicity and convulsion induction take a look at of the brand new quinolone antibacterial agent (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxyl ic acid hemihydrate in laboratory animals.

(S)-10-[(S)-(8-Amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxyli c acid hemihydrate (CAS 151390-79-3, DV-7751a) a brand new quinolone antibacterial agent, was examined for LD50 worth, phototoxicity and convulsion inducing potential in laboratory animals.

A single oral administration of DV-7751a induced comfortable stool in rats at 1000 and 2000 mg/ kg and in monkeys at 250 mg/kg and vomiting in monkeys at 500 mg/kg or extra. A single intravenous administration induced a lower in locomotor exercise, respiratory despair, convulsion, pulmonary edema and dying in rats and mice.

The LD50 values with oral administration have been greater than 2000 mg/ kg for rats and mice and greater than 250 mg/kg for monkeys, and people with intravenous administration have been 164.Three mg/kg for rats of each sexes at an injection price of two ml/min, 118.eight mg/kg for male rats and 104 to 125 mg/kg for feminine rats at 0.5 ml/min, and 184.7 mg/kg for male mice and 187.Four mg/kg for feminine mice.

DV-7751a confirmed very weak phototoxicity in mice after single oral administration of 600 mg/kg, adopted by UVA irradiation, however no convulsion after oral administration of 200 or 1000 mg/kg together with 4-biphenylacetic acid at 400 mg/kg.

Postoperative analysis of EC/IC bypass surgery–long-term observe up research by donor artery compression take a look at.

Focal cerebral vascular dependency of donor arteries was evaluated in 45 sufferers who had undergone EC/IC bypass surgical procedure. Throughout EEG recording, digital compression was utilized to the anastomosed donor superficial temporal artery (STA) on the preauricular area. The looks of sluggish waves on the EEG recording suggests hypofunction of the native mind.

In instances displaying constructive response to the STA compression take a look at, we recommend that the blood provide by way of STA is an important collateral path to the ischemic mind. The take a look at was periodically repeated within the postoperative follow-up interval for a imply of seven years. Eleven instances (24%) confirmed constructive leads to the STA compression take a look at in the course of the long-term postoperative follow-up interval

FluroBronze DNA Marker 1
57939 50 mcg
EUR 108.02
Description: Part E

FluroBronze Hi-Range DNA Marker
99331 50 mcg
EUR 122.9
Description: Part E

FluroBronze Mid-Range DNA Marker
32462 50 mcg
EUR 91.94
Description: Part E

PCR Ladder
77305 10 mcg
EUR 15.91
Description: Part E

PCR Ladder
77305-1 50 mcg
EUR 50.55
Description: Part E

SafeDye PCR Ladder
64935 50 mcg
EUR 88.69
Description: Part E

Apex PCR DNA Ladder
42-432 1 x 0.5ml/Unit
EUR 72.48
Description: 100 Lanes, 100-3,000bp

Apex PCR DNA Ladder
42-433 1 x 1.0ml/Unit
EUR 144.97
Description: 200 Lanes, 100-3,000bp

Apex PCR DNA Ladder
42-434 1 x 2.5ml/Unit
EUR 362.3
Description: 500 Lanes, 100-3,000bp

1kb Ladder
MBS278040-100Reactions 100Reactions
EUR 150

DNA LADDER (100bp)
IB01301 50uG/500uL
EUR 59.65
Description: [FR]

DNA LADDER (100bp)
IB01302 50uG/500uL
EUR 56.1
Description: (NO LOADING DYE) [FR]

100bp Ladder
MBS278039-100Reactions 100Reactions
EUR 150

Fluorescent 20 bp DNA Ladder
M-232L 5 x 500µl
EUR 415.2
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Fluorescent 20 bp DNA Ladder
M-232S 500µl
EUR 103.7
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Fluorescent 50 bp DNA Ladder
M-233L 5 x 500µl
EUR 346
Description: ready-to-use, orange, green fluorescent

Fluorescent 50 bp DNA Ladder
M-233S 500µl
EUR 86.6
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M-234L 5 x 500µl
EUR 288.4
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M-234S 500µl
EUR 72.1
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Fluorescent 500 bp DNA Ladder
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Fluorescent 500 bp DNA Ladder
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EUR 52
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Fluorescent 1 kb DNA Ladder
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EUR 207.7
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Fluorescent 1 kb DNA Ladder
M-237S 500µl
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1 kb Ladder
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VC1kb DNA Ladder, 50µg
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DNA LADDER (1KB)
IB01351 50uG/500uL
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Fluorescent Low Range DNA Ladder
M-222L 5 x 500µl
EUR 346
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Fluorescent Low Range DNA Ladder
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EUR 86.6
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M-223L 5 x 500µl
EUR 288.4
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EUR 72.1
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VC100bp DNA Ladder, 50µg
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100bp DNA ladder
9K-004-0002 0.5ml
EUR 260.98

100bp DNA ladder
TBS4030-0.5mL 0.5 ml
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100bp DNA ladder
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EUR 110

Fluorescent High Range DNA Ladder
M-224L 5 x 500µl
EUR 230.7
Description: ready-to-use, blue / blue, green fluorescent

Fluorescent High Range DNA Ladder
M-224S 500µl
EUR 57.6
Description: ready-to-use, blue / blue, green fluorescent

Fluorescent Long Range DNA Ladder
M-225L 5 x 500µl
EUR 403.7
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Fluorescent Long Range DNA Ladder
M-225S 500µl
EUR 100.9
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SafeDye 500bp Ladder
27107 50 mcg
EUR 110.24
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SafeDye 100bp Ladder
33902 50 mcg
EUR 92.28
Description: Part E

VC 50bp DNA Ladder, 50µg
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1 kb DNA Ladder
Z6030002 100 lanes
EUR 158

20 bp DNA Ladder
M-212L 5 x 500µl
EUR 346
Description: ready-to-use, orange

20 bp DNA Ladder
M-212S 500µl
EUR 86.6
Description: ready-to-use, orange

50 bp DNA Ladder
M-213L 5 x 500µl
EUR 288.4
Description: ready-to-use, orange

50 bp DNA Ladder
M-213S 500µl
EUR 72.1
Description: ready-to-use, orange

1 kb DNA Ladder
M-217L 5 x 500µl
EUR 172.8
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1 kb DNA Ladder
M-217S 500µl
EUR 43.2
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1 kb DNA Ladder
M1157-500 each
EUR 333.6

1 kb DNA Ladder
RM19005 500μL
EUR 114

1 Kb DNA Ladder
DL006 each
EUR 17.3

1 Kb DNA Ladder
DL006S each
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50 bp DNA Ladder
DL008 each
EUR 45

50 bp DNA Ladder
DL008S each
EUR 2.2

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1 kb DNA Ladder
MBS9143981-25mL 2.5mL
EUR 450

1 kb DNA Ladder
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50 bp DNA Ladder
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EUR 215

50 bp DNA Ladder
MBS433533-5x005mg 5x0.05mg
EUR 815

100 bp DNA Ladder
M-214L 5 x 500µl
EUR 240.4
Description: ready-to-use, orange / blue

100 bp DNA Ladder
M-214S 500µl
EUR 60.1
Description: ready-to-use, orange / blue

200 bp DNA Ladder
M-215L 5 x 500µl
EUR 230.7
Description: ready-to-use, blue / blue

200 bp DNA Ladder
M-215S 500µl
EUR 57.6
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500 bp DNA Ladder
M-216L 5 x 500µl
EUR 172.8
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500 bp DNA Ladder
M-216S 500µl
EUR 43.2
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100 bp DNA Ladder
MD104-01 250 μl
EUR 18.64

100 bp DNA Ladder
MD104-02 500 μl
EUR 29

100 bp DNA Ladder
M1158-500 each
EUR 333.6

100 bp DNA Ladder
RM19007 500μL
EUR 138

100 bp DNA Ladder
DL007 each
EUR 17.3

100 bp DNA Ladder
DL007S each
EUR 1.2

100 bp DNA Ladder
MBS9143983-05mL 0.5mL
EUR 165

100 bp DNA Ladder
MBS9143983-25mL 2.5mL
EUR 340

100 bp DNA Ladder
MBS9143983-5x25mL 5x2.5mL
EUR 1345

100 bp DNA Ladder
MBS433528-005mg 0.05mg
EUR 175

100 bp DNA Ladder
MBS433528-5x005mg 5x0.05mg
EUR 640

100 bp DNA Ladder
MD104-01-50rxns 50 rxns
EUR 19.3

100 bp DNA Ladder
MD104-02-100rxns 100 rxns
EUR 30.03

100 bp DNA Ladder
RK30193 500μL
EUR 130.8

100bp DNA ladder (200 Lanes)
MBT049-200LN 1 unit
EUR 142.29
Description: 100bp DNA ladder (200 Lanes)

Apex DNA Ladder I
42-427 1 x 1.0ml/Unit
EUR 295.59
Description: 200 Lanes, 200-12,000bp

Apex DNA Ladder I
42-428 1 x 2.5ml/Unit
EUR 463.43
Description: 500 Lanes, 200-12,000bp

Apex DNA Ladder II
42-429 1 x 0.5ml/Unit
EUR 90.91
Description: 100 Lanes, 100-1,000bp

Apex DNA Ladder II
42-430 1 x 1.0ml/Unit
EUR 181.82
Description: 200 Lanes, 100-1,000bp

Apex DNA Ladder II
42-431 1 x 2.5ml/Unit
EUR 454.32
Description: 500 Lanes, 100-1,000bp

PRESTAINED PROTEIN LADDER
IB01210 245kDa
EUR 258.78

VC100bp Plus DNA Ladder, 50µg
NL1405 each Ask for price

Apex DNA Ladder III
42-424 1 x 1.0ml/Unit
EUR 187.26
Description: 200 Lanes, 80bp - 10Kb

Apex DNA Ladder III
42-425 1 x 2.5ml/Unit
EUR 467.98
Description: 500 Lanes, 80bp - 10Kb

Apex 500bp DNA Ladder
19-113 1ml/Unit
EUR 132.31
Description: 200 Gel Lanes, 500bp - 5kb

*Low Range DNA Ladder
IDNALDRLEL500UL each
EUR 157
Description: *Low Range DNA Ladder

*Mid Range DNA Ladder
IDNALDRMEL500UL each
EUR 135
Description: *Mid Range DNA Ladder

Low Range DNA Ladder
M-202L 5 x 500µl
EUR 317.3
Description: ready-to-use, orange / blue

Low Range DNA Ladder
M-202S 500µl
EUR 79.2
Description: ready-to-use, orange / blue

Mid Range DNA Ladder
M-203L 5 x 500µl
EUR 259.4
Description: ready-to-use, orange / blue
Alejandra

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